Deciphering the genetic basis of sex differentiation in silver-lipped pearl oyster ( <i>Pinctada maxima</i>) based on integrative transcriptomic analysis.

ABSTRACT: The silver-lipped pearl oyster ( Pinctada maxima) is the largest and most commercially valuable pearl-producing oyster, renowned for its ability to generate large, lustrous pearls. This species is a sequential hermaphrodite, with pearl production displaying notable sexual dimorphism. Consequently, understanding the molecular mechanisms governing sex determination and differentiation is crucial for advancing breeding strategies in the pearl oyster industry. To elucidate these mechanisms, this study conducted integrative transcriptomic analyses of P. maxima gonadal tissues using isoform sequencing (Iso-seq) and RNA sequencing (RNA-seq). Comparative analysis of ovarian and testicular tissues identified 2 768 differentially expressed genes (DEGs). Gene co-expression network analy

SUBMITTER: Li ZJ 

PROVIDER: S-EPMC12000136 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature