Social isolation and poor mental health in young people: testing genetic and environmental influences in a longitudinal cohort study.

ABSTRACT: We assessed genetic and environmental influences on social isolation across childhood and the overlap between social isolation and mental health symptoms including depression symptoms, conduct problems, and psychotic-like experiences from adolescence to young adulthood. Participants included 2,232 children from the Environmental Risk Longitudinal Twin Study. Social isolation was measured at ages 5, 7, 10, 12, and 18. A Cholesky decomposition was specified to estimate the genetic and environmental influences on social isolation across ages 5, 7, 10, and 12. An independent pathway model was used to assess additive genetic (A), shared environmental (C), and non-shared environmental (E) influences on the overlap between social isolation and mental health problems from age 12 to 18. Genetic and

SUBMITTER: Thompson KN 

PROVIDER: S-EPMC12000192 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature