J-type assembled Pt(IV)-coordinated carbon dots for near-infrared light-triggered pyroptosis.

ABSTRACT: Near-infrared (NIR) light-triggered pyroptosis based on biocompatible Pt(IV)-coordinated nanomedicine for tumor precision therapy is challenging. Here, we disclose a supramolecular approach to construct a hollow-spherical supra-(carbon dots) (HS-Pt-CDs) via ultrasound-assisted J-type assembly of Pt(IV)-coordinated carbon dots (Pt-CDs). The peculiar assembling behaviors arise from the steric hindrance and lattice distortion in the bowl-like Pt-CDs caused by the coordination of Pt(IV) atoms among the sp² domains, which result in around 240 nm red-shifted absorption bands and promoting charge separation in the NIR region due to strong inter-molecular charge transfer (CT) in HS-Pt-CDs. The results reveal that HS-Pt-CDs exhibit excellent NIR light-activated photocatalytic capacities,

SUBMITTER: Guo D 

PROVIDER: S-EPMC12000447 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature