Impact of a horizontally transferred Helitron family on genome evolution in Xenopus laevis.

ABSTRACT:

Background

Within eukaryotes, most horizontal transfer of genetic material involves mobile DNA sequences and such events are called horizontal transposable element transfer (HTT). Although thousands of HTT examples have been reported, the transfer mechanisms and their impacts on host genomes remain elusive.

Results

In this work, we carefully annotated three Helitron families within several Xenopus frog genomes. One of the Helitron family, Heli1Xen1, is recurrently involved in capturing and shuffling Xenopus laevis genes required in early embryonic development. Remarkably, we found that Heli1Xen1 is seemingly expressed in X. laevis and has produced multiple genomic polymorphisms within the X. laevis population. To identify the origin of Heli1Xen1, we searched its consensus se

SUBMITTER: Li Z 

PROVIDER: S-EPMC12001565 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature