Bayesian inference by visuomotor neurons in the prefrontal cortex.

ABSTRACT: Perceptual judgments of the environment emerge from the concerted activity of neural populations in decision-making areas downstream of the sensory cortex. When the sensory input is ambiguous, perceptual judgments can be biased by prior expectations shaped by environmental regularities. These effects are examples of Bayesian inference, a reasoning method in which prior knowledge is leveraged to optimize uncertain decisions. However, it is not known how decision-making circuits combine sensory signals and prior expectations to form a perceptual decision. Here, we study neural population activity in the prefrontal cortex of macaque monkeys trained to report perceptual judgments of ambiguous visual stimuli under two different stimulus distributions. We isolate the component of the neural popu

SUBMITTER: Langlois TA 

PROVIDER: S-EPMC12002263 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature