Structure of ATP synthase from an early photosynthetic bacterium <i>Chloroflexus aurantiacus</i>.

ABSTRACT: F-type ATP synthase (F₁F_O) catalyzes proton motive force-driven ATP synthesis in mitochondria, chloroplasts, and bacteria. Different from the mitochondrial and bacterial enzymes, F₁F_O from photosynthetic organisms have evolved diverse structural and mechanistic details to adapt to the light-dependent reactions. Although complete structure of chloroplast F₁F_O has been reported, no high-resolution structure of an F₁F_O from photosynthetic bacteria has been available. Here, we report cryo-EM structures of an intact and functionally competent F₁F_O from Chloroflexus aurantiacus (CaF₁F_O), a filamentous anoxygenic phototrophic bacterium from the earliest

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12002316 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature