Genotypic drug resistance and transmission clusters of Mycobacterium tuberculosis isolates among Ethiopian returnees from Saudi Arabia.

ABSTRACT:

Background

Human migration significantly contributes to the global spread of infectious diseases. In recent years, Ethiopia has experienced an increased influx of returnees from the Kingdom of Saudi Arabia. These migrants were often held in densely populated and inadequately ventilated detention centers and faced a heightened risk of tuberculosis transmission. This study investigates the genotypic drug resistance and transmission clusters of M. tuberculosis among returnees from various detention centers in the Kingdom of Saudi Arabia. Whole genome sequencing (WGS) is employed to characterize the genotypic drug resistance patterns and transmission clusters of M. tuberculosis isolates in presumptive TB cases.

Methodology

Following symptom screening for presumptive TB, sputum s

SUBMITTER: Tilahun M 

PROVIDER: S-EPMC12002542 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature