Incidence, prevalence, and mortality of sarcoidosis in England: a population-based study.

ABSTRACT:

Background

The epidemiology of sarcoidosis in England is largely uncharted, with no population-level prevalence data and outdated incidence and mortality estimates. Our objective was to investigate contemporary trends in incidence, prevalence, and mortality.

Methods

This cohort study used primary care data from the UK Clinical Practice Research Datalink (CPRD), linked to secondary-care and national death registration. Patients aged ≥18 with sarcoidosis were identified using primary care codes. Age-and-sex standardised incidence and prevalence were calculated. Standardised mortality ratios (SMRs) compared mortality with the general population. A matched non-sarcoidosis cohort was constructed within CPRD, and Poisson regression compared all-cause mortality between incident cas

SUBMITTER: Bechman K 

PROVIDER: S-EPMC12002749 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature