Limitations of human t-lymphotropic virus type 1 antibody testing in hospitals of endemic regions in China.

ABSTRACT:

Purpose

This study aims to evaluate the sensitivity and specificity of human T-lymphotropic virus type 1 (HTLV-1) antibody testing within hospitals located in HTLV-1 endemic areas of China.

Method

We performed a retrospective analysis of the clinical records and laboratory results for 1,147 patients who underwent HTLV-1 antibody testing using the Wantai HTLV-1 antibody detection kit and Polymerase Chain Reaction (PCR) testing for HTLV-1 nucleic acids, at Fujian Medical University Union Hospital between 2017 and 2023.

Result

The study population comprised 674 males (58.8%) and 473 females (41.2%), with an age distribution ranging from 7 to 86 years, and a median age of 50 years. Of the patients, 81 (7.1%) tested positive for HTLV-1 antibodies, including 39 males and 42

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12003307 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature