Sex differences in outcomes and time to treatment in stroke patients treated with tenecteplase.

ABSTRACT:

Introduction

A better understanding of sex-related differences remains key to improve stroke care for women. We aimed to assess the differences of prognosis, symptomatic intracranial hemorrhage (sICH) rates and process times between men and women suffering from ischemic stroke.

Patients and methods

We performed a sex-based retrospective analysis of the French Tenecteplase Treatment in Stroke multicentric registry from 2015 to 2021. We assessed sex differences in terms of 3-month good neurological outcome (defined as modified Rankin score ⩽ 2 or back to its pre-stroke value), occurrence of sICH and process times with multivariable logistic regression analyses.

Results

1339 consecutive patients (684 women, 655 men) received tenecteplase between 2015 and 2021, among whom

SUBMITTER: Yger M 

PROVIDER: S-EPMC12003326 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature