When Weight Matters: How Obesity Impacts Reproductive Health and Pregnancy-A Systematic Review.

ABSTRACT:

Purpose of review

This systematic review evaluates the impact of obesity on both male and female reproductive health, assisted reproductive technology (ART) outcomes, and pregnancy-related complications, providing a comprehensive synthesis of the evidence.

Recent findings

Obesity is a critical factor adversely affecting reproductive health, ART success rates, and pregnancy outcomes. Recent studies indicate hormonal disruptions, metabolic syndrome, and epigenetic modifications as central mechanisms linking obesity to infertility and adverse pregnancy results. A systematic search adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines included 35 studies, focusing on obesity-related reproductive outcomes. The review highlights tha

SUBMITTER: Barbouni K 

PROVIDER: S-EPMC12003489 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature