Comprehensive assessment of supratentorial and infratentorial volumes in infants with myelomeningocele with and without Chiari malformation type II.

ABSTRACT:

Purpose

Chiari malformation type II (CM-II) is a congenital anomaly commonly associated with myelomeningocele (MMC), a severe form of open spina dysraphism. This study aimed to evaluate both supratentorial and infratentorial volumes in MMC infants with and without CM-II.

Methods

We conducted a single-center, retrospective study of 52 MMC infants treated between April 2006 and July 2023. Infants were classified as non-CM-II or CM-II based on the presence of cerebellar displacement. All patients underwent computed tomography (CT) at 0 months of age. Volumetric parameters included intracranial volume (ICV), lateral ventricles volume (LVV), posterior cranial fossa volume (PCFV), cerebellum volume (CBMV), and brainstem volume (BSV). LVV represented supratentorial structures, whil

SUBMITTER: Hashimoto H 

PROVIDER: S-EPMC12003494 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature