Dietary patterns and colorectal cancer: a multicenter case-control study in an Iranian population.

ABSTRACT: Evidence on the association between dietary patterns (DPs) and colorectal cancer (CRC) is inconclusive. Thus, we aimed to evaluate it in an Iranian population. We analyzed data from a multicenter hospital-based case-control study conducted in Iran during 2017-2020. We derived a posteriori DPs using principal component factor analysis, and used reduced rank regression (RRR) to derive a DP high in unhealthy fats. We estimated adjusted odds ratios (ORs) and corresponding 95% confidence intervals (CIs) for the association between quartiles of DPs and CRC. False discovery rate (FDR)-corrected p-values were computed. We included 865 CRC cases and 3,204 controls in the study. After FDR correction, the Western-type diet (OR_Q4vsQ1 4.15; 95% CI 2.49-6.90; p_trend < 0.001) identi

SUBMITTER: Sassano M 

PROVIDER: S-EPMC12003644 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature