Extreme events in gene regulatory networks with time-delays.

ABSTRACT: This work explores distinct complex dynamics of simplified two nodes of coupled gene regulatory networks with multiple delays in two self-inhibitory and mutually activated genes. We have identified the emergence of extreme events within a specific range of system parameter values. A detailed analysis of the time delay-induced emergence of extreme events is illustrated using bifurcation analysis, two-parameter phase diagrams, return maps, temporal plots, and probability density functions. The reasons behind the advent of extreme events are discussed in detail, with possible analogies to simplified two nodes of gene regulatory networks. The occasional large-amplitude bursting originated in the system via interior crisis-induced intermittency, Pomeau-Manneville intermittency, and the breakdow

SUBMITTER: Vinoth S 

PROVIDER: S-EPMC12003715 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature