Association of liver fibrosis-4 index with functional outcomes in chinese patients with acute ischemic stroke undergoing mechanical thrombectomy.

ABSTRACT: This study aimed to investigate the association between the Fibrosis-4 (FIB-4) index and functional outcomes and hemorrhagic complications in patients with large vessel occlusion acute ischemic stroke (LVO-AIS) treated with mechanical thrombectomy (MT). In this single-center retrospective cohort study, we consecutively enrolled patients with LVO-AIS who underwent MT between January 2018 and February 2024. The primary endpoint was poor functional outcome at 90 days (modified Rankin Scale score 3-6). Secondary endpoints included hemorrhagic transformation (HT) and symptomatic intracranial hemorrhage (sICH). Multivariable logistic regression models and restricted cubic spline analyses were used to evaluate the association between FIB-4 index and outcomes after adjusting for potential confound

SUBMITTER: Gao W 

PROVIDER: S-EPMC12003717 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature