Association of carotid atherosclerosis, perivascular adipose tissue, and stiffness by ultrasound assessment in young adults with ischemic stroke.

ABSTRACT: In the last decade, the incidence of stroke among young adults has risen globally. The relevance of carotid intima-media thickness (IMT) and plaque in predicting ischemic stroke (IS) in this population remains uncertain. This study investigated the relationship between ultrasound-evaluated carotid wall properties and occurrence and severity of IS in young adults. Young adults (n = 147) aged 18-50 years with IS and 294 age- and sex-matched controls were included. Ultrasound-assessed variables included carotid atherosclerosis, perivascular adipose tissue, and arterial stiffness. Ultrasound parameters included IMT, plaque presence, extra-media thickness (EMT), and flow augmentation index (FAI). Multivariate and ROC curve analyses were conducted. All ultrasound parameters were elevated in the

SUBMITTER: Xu X 

PROVIDER: S-EPMC12003753 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature