Untangling discrepancies between cerebrovascular autoregulation correlation coefficients: An exploration of filters, coherence and power.

ABSTRACT: Cerebrovascular autoregulation (CAR) maintains stable cerebral perfusion by adjusting arteriole diameters in response to slow pressure fluctuations. Various CAR correlation coefficients-PRx (based on intracranial pressure-ICP), Mx (based on transcranial doppler-TCD), and COx/THx (based on near-infrared spectroscopy-NIRS)-are used interchangeably despite fundamental differences. 566 hours of ICP, NIRS, and TCD data from 38 traumatic brain injury (TBI) patients were assessed. The intercorrelation between CAR correlation coefficients was compared in relation to: (1) The impact of different filtering methods (to minimize noise); (2) The impact of slow wave power (i.e., magnitude of incoming trigger); (3) The impact of coherence (i.e., to what extent can the power of slow waves explain the chan

SUBMITTER: Bogli SY 

PROVIDER: S-EPMC12004267 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature