Analysis and prediction of contralateral central lymph node metastasis risk in unilateral papillary thyroid carcinoma with ipsilateral lateral cervical lymph node: a retrospective clinical study.

ABSTRACT:

Background

Papillary thyroid carcinoma (PTC) often metastasizes to lymph nodes, increasing recurrence risk and reducing survival. This study identifies predictors for contralateral central lymph node metastasis (Cont-CLNM) in unilateral PTC patients with ipsilateral lateral cervical lymph node metastasis (Ipsi-LLNM).

Methods

We retrospectively analyzed data, preoperative ultrasound features, and thyroglobulin (Tg) levels in unilateral PTC patients with Ipsi-LLNM treated at the Thyroid Surgery Department of Nanjing Drum Tower Hospital from August 2017 to August 2024. Least absolute shrinkage and selection operator (LASSO) regression was used for variable selection, with independent t-tests and Chi-squared tests assessing differences. Logistic regression analyses identi

SUBMITTER: Dai L 

PROVIDER: S-EPMC12004314 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature