Detoxification of coumarins by rumen anaerobic fungi: insights into microbial degradation pathways and agricultural applications.

ABSTRACT:

Background

Coumarins are toxic phytochemicals found in a variety of plants and are known to limit microbial degradation and interfere with nutrient cycling. While the degradation of coumarins by fungi has been studied in an environmental context, little is known about their degradation in the gastrointestinal system of herbivores after ingestion.

Results

In this study, we investigated in vitro fermentation by microbial enrichment, transcriptome sequencing, and high-resolution mass spectrometry to evaluate the ability of rumen anaerobic fungi to degrade coumarins. The results showed that despite the low abundance of anaerobic fungi in the rumen microbiota, they were able to effectively degrade coumarins. Specifically, Pecoramyces ruminantium F1 could tolerate coumarin concent

SUBMITTER: Li Y 

PROVIDER: S-EPMC12004625 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature