Clinical and magnetic resonance imaging features in acute ischemic stroke with early wallerian degeneration: a case-control study.

ABSTRACT:

Background

In advanced stages, Wallerian degeneration (WD) after cerebral infarction appears as an abnormality in the descending corticospinal tract on T2-weighted images. However, early WD in this region is detectable via diffusion-weighted imaging (DWI) within the first 14 days. We aimed to investigate the clinical and imaging characteristics of early WD using patient data.

Methods

We retrospectively reviewed clinical characteristics and magnetic resonance imaging (MRI) features of 105 acute stroke cases. Early WD factors, including the time from symptom onset to MRI scan, Brunnstrom stage at admission and discharge, risk factors for ischemic stroke, classification per the Stop Stroke Study Trial of Org 10,172 in Acute Stroke Treatment classification, infarct location, res

SUBMITTER: Ota K 

PROVIDER: S-EPMC12004872 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature