<i>Burkholderia cenocepacia</i>-mediated inhibition of <i>Staphylococcus aureus</i> growth and biofilm formation.

ABSTRACT: Staphylococcus aureus asymptomatically colonizes the nasal cavity and pharynx of up to 60% of the human population and, as an opportunistic pathogen, can breach its normal habitat, resulting in life-threatening infections. S. aureus infections are of additional concern for populations with impaired immune function such as those with cystic fibrosis (CF) or chronic granulomatous disease. Multi-drug resistance is increasingly common in S. aureus infections, creating an urgent need for new antimicrobials or compounds that improve efficacy of currently available antibiotics. S. aureus biofilms, such as those found in the lungs of people with CF and in soft tissue infections, are notoriously recalcitrant to antimicrobial treatment due to the characteristic metabolic

SUBMITTER: Brandt TJ 

PROVIDER: S-EPMC12004965 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature