Primary Results from IMscin002: A Study to Evaluate Patient Preferences and Perceptions of Health Care Professionals for Atezolizumab Subcutaneous Versus Intravenous for the Treatment of NSCLC.

ABSTRACT:

Introduction

Subcutaneous (SC) atezolizumab, a co-formulation containing atezolizumab and recombinant human hyaluronidase PH20), has been approved for use in more than 50 countries for the same indications as intravenous (IV) atezolizumab. IMscin002 (NCT05171777), a phase 2, randomized, open-label, crossover trial, investigated patient preferences and health care professionals' (HCPs') perceptions of atezolizumab SC versus IV for the treatment of NSCLC; we report the primary results of IMscin002.

Methods

Patients with programmed death-ligand 1-positive resected NSCLC who had completed adjuvant chemotherapy without evidence of recurrence, and chemotherapy-naive patients with programmed death-ligand 1-high metastatic NSCLC were randomized 1:1 to arm A (atezolizumab SC then ate

SUBMITTER: Cappuzzo F 

PROVIDER: S-EPMC12005273 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature