Cone-beam computed tomography reconstruction for a commercial proton beam therapy system.

ABSTRACT:

Background & purpose

Cone-beam computed tomography (CBCT) images are used in image-guided radiotherapy to track anatomical changes throughout treatment and to set up patients to ensure accurate delivery of therapeutic radiation at each treatment session. An offline method of CBCT reconstruction workflow, operating on 2D projection images and specific to the imaging system in question, is needed for many image optimisation studies. Here we present a methodology to reconstruct CBCT images from these data for a commercial proton beam therapy machine, accounting for the variation in exposure and beam hardening from filtration due to gantry rotation during CBCT acquisition.

Materials & methods

Projection data of solid water phantoms were acquired to model bow-tie filter motion an

SUBMITTER: Lindsay JWH 

PROVIDER: S-EPMC12005303 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature