Evaluation and characterization of framycetin sulphate loaded hydrogel dressing for enhanced wound healing.

ABSTRACT:

Background

Hydrogels loaded with antibiotics can be an effective drug delivery systemfor treating skin diseases or conditions such asinburns and wound healing.

Objectives

The current research work was planned to preparea hydrogel dressing for an effective wound healing. The hydrogel formulation was aimed to provide sustained drug release, reducing the frequency of repeated applying the transdermal drug formulation or patch.

Methods

Different polymers, polyvinyl alcohol, sodium alginate, and polyvinyl pyrrolidonein varying ratios were used to prepare hydrogels by freeze-thawing method. The prepared hydrogel formulations were loaded with framycetinsulphate (FC-S), a topical aminoglycoside.

Results

Swelling behaviour, drug release pattern, wereinvestigated.Equilib

SUBMITTER: Wu Z 

PROVIDER: S-EPMC12005552 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature