Expected outcomes of stratified post-donation testing in whole blood donation in England: A discrete event simulation modeling study.

ABSTRACT:

Background

In England, blood donors with low hemoglobin concentration are deferred following on-session testing to prevent donations below regulatory thresholds, thereby protecting donors' health and blood supply quality. However, deferrals are costly, time-consuming and may discourage donors. Post-donation testing (PDT), where hemoglobin levels are measured after donation, offer potential alternatives as used in some European countries.

Study design and methods

We compared four PDT strategies to the current approach: (A) no on-session testing, (B) on-session testing if low hemoglobin at previous visit, (C) on-session testing if low/medium hemoglobin at previous visit, all with delayed reinvitation if low hemoglobin at previous donation, and (D) on-session testing if low/med

SUBMITTER: Qi H 

PROVIDER: S-EPMC12005575 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature