Exploring the associations between data-driven insomnia disorder combined with mild anxiety or/and depressive symptoms and the efficacy of Cognitive-Behavioral Therapy for insomnia.

ABSTRACT:

Objectives

The endophenotype of insomnia disorder is complex and the treatment is not targeted. The data-driven typing method might provide some bases for precise treatment. The present study was based on a post hoc analysis, aiming to explore the association between subtypes of insomnia disorder and the efficacy of cognitive-behavioral therapy for insomnia (CBT-I).

Methods

The present study was conducted on data of 118 patients with chronic insomnia disorder combined mild anxiety or/and depressive symptoms, who had completed an 8-week randomized controlled trial of CBT-I vs CBT-I plus (CBT-I combined with modules targeting anxiety and depressive symptoms). The silhouette coefficient determined the optimal number of clusters, and a K-means clustering analysis was performed.

SUBMITTER: Lyu D 

PROVIDER: S-EPMC12005858 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature