Residue of allocryptopine and protopine in tissues and eggs of laying hens using ultra-high performance liquid chromatography-tandem mass spectrometry.

ABSTRACT: The residues of allocryptopine (ALL) and protopine (PRO) in the eggs and tissues of laying hens from the veterinary drug Bopp Total Alkali Powder® were evaluated. UPLC-MS/MS technology was used to accurately determine these components. The study found that at a dose of 400 mg/kg, PRO in eggs reached a peak of 2.8 µg/kg on the seventh day of administration and was undetectable five days after stopping the medication. ALL was not detected throughout the study. At a dose of 2000 mg/kg, one day after stopping the medication, the residues of PRO and ALL reached 16.72 µg/kg and 8.61 µg/kg, respectively. Seven days after stopping the medication, PRO was undetectable, but there was still a residue of ALL. Tissue samples showed that two hours after stopping the medication, the concentrations of bot

SUBMITTER: Liu M 

PROVIDER: S-EPMC12005882 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature