Gastrointestinal Manifestations and Associated Comorbidities in Children with Autism Spectrum Disorder: A Cross-sectional Analysis from South India.

ABSTRACT:

Background

Gastrointestinal (GI) symptoms are frequently reported in children with autism spectrum disorder (ASD) and may significantly impact behavior, sleep, adaptive functioning, and the severity of autism. This study aims to explore the relationship between GI symptoms and these factors in children with ASD.

Methods

We investigated 96 children and adolescents with ASD aged 3-18 years attending an autism clinic in South India. Parents were interviewed using a semi-structured proforma that gathered information on GI symptoms, sociodemographic details, medical history, and treatment history. Behavioral problems were assessed using the Strengths and Difficulties Questionnaire-2 (SDQ-2), ASD severity was measured using the Indian Scale for Assessment of Autism (ISAA), and sle

SUBMITTER: Prabhakaran N 

PROVIDER: S-EPMC12006118 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature