Oral anticoagulant timing and hospitalization in newly diagnosed nonvalvular atrial fibrillation patients.

ABSTRACT:

Background

Non-valvular atrial fibrillation (NVAF) significantly increases ischemic stroke and systemic embolism (SE) risks. Despite the proven efficacy of oral anticoagulants (OAC) in reducing these risks, their underutilization highlights a gap in clinical practice. This study examined OAC utilization patterns within the first year after NVAF diagnosis in patients without prior OAC use and the association between the timing of OAC initiation and the risk of all-cause and stroke/SE-specific hospitalizations.

Methods

A retrospective cohort study was conducted using data from the Premier Healthcare Database and linked claims from 1/1/2017-3/31/2021. Patients newly diagnosed with NVAF, without prior OAC use, were included.

Results

Of 23,148 adults with newly diagnosed N

SUBMITTER: Cui C 

PROVIDER: S-EPMC12006160 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature