Global and regional estimates of vaccine-associated herpes zoster and their related vaccines from 1969 to 2023.

ABSTRACT: Vaccine-induced immunosuppression can reactivate the varicella-zoster virus, potentially leading to the development of herpes zoster. However, the literature on this topic is inconsistent, resulting in limited clarity. Therefore, we aimed to enhance our understanding of vaccine-associated herpes zoster and establish guidelines for future research, utilizing a global database to improve global public health. We investigated vaccine-associated adverse events in herpes zoster using reports (~ 13 million reports) from the WHO international pharmacovigilance database. Data were analyzed for the global number of reports, reported odds ratios (ROR), and information components (IC) to determine the potential association between 18 vaccines and vaccine-associated herpes zoster reports in nearly 170

SUBMITTER: Jeong J 

PROVIDER: S-EPMC12006434 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature