Use of Freestyle Libre 2.0 in children with type 1 diabetes mellitus and elevated HbA_1c: Extension phase results after a 12-week randomized controlled trial.

ABSTRACT:

Aim

To investigate extension phase outcomes with intermittently scanned continuous glucose monitoring (isCGM 2.0) in children with type 1 diabetes mellitus (T1DM) and elevated HbA_1c (7.5-12.2% [58-110 mmol/mol]).

Methods

One hundred children with T1DM aged 4-13 years were initially in a 12-week randomised controlled trial (RCT) comparing glycaemic outcomes with isCGM 2.0 (intervention group, n = 49) with self-monitored blood glucose (Control group, n = 51). After the 12-week RCT both groups were offered an extension phase with isCGM 2.0 for another 12 weeks. HbA_1c, CGM metrics, psychological outcomes and device utilization attitudes were measured.

Results

After the initial 12-week RCT, 66 participants completed this 12-week extension: 36/49 (73%)

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12006559 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature