Associations of mechanical power, ventilatory ratio, and other respiratory indices with mortality in patients with acute respiratory distress syndrome undergoing pressure-controlled mechanical ventilation.

ABSTRACT:

Background

Mechanical power (MP) and ventilatory ratio (VR) are crucial metrics in the management of acute respiratory distress syndrome (ARDS). This study aimed to evaluate the impact of these factors on ICU mortality in patients with ARDS undergoing pressure-controlled ventilation.

Methods

In this retrospective study, we included 600 adult patients with ARDS who required mechanical ventilation for > 48 h between March 2018 and February 2021 in a tertiary referral hospital in Korea. The MP was calculated using Becher's simplified equation, and the VR was determined using standard formulas. The ventilatory parameters were measured hourly during the first 12 h of ventilation. Clinical characteristics, ventilator settings, and outcomes were compared between the survivors and n

SUBMITTER: Kim TW 

PROVIDER: S-EPMC12006839 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature