Development of Dual-Function Microelectronic Fibers for pH and Temperature Sensing: Toward <i>In Vivo</i> and Wearable Applications.

ABSTRACT: Temperature plays a crucial role in biological functions in normal physiological and pathological states and is intricately linked with chemical dynamics in vivo at the cellular, circuit, and system levels. Despite advances in temperature measurement technologies for internal monitoring, systems capable of simultaneously tracking localized temperature and chemical changes are still underdeveloped. In this study, we introduce dual-sensing hybrid fibers with a miniature footprint of <400 μm in diameter, fabricated using the thermal drawing process. These fibers exhibit precise temperature sensitivity, detecting changes as small as 0.5 °C, and demonstrate highly sensitive and reversible pH detection, a critical physiological parameter. Furthermore, through laser micromachining and surf

SUBMITTER: Kubo M 

PROVIDER: S-EPMC12006951 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature