Estimating the potential impact of surveillance test-and-treat posts to reduce malaria in border regions in sub-Saharan Africa: a modelling study.

ABSTRACT:

Background

The last malaria cases in near-elimination settings are often found in international border regions due to the presence of hard-to-reach populations, conflict, uneven intervention coverage, and human migration. Test-and-treat border posts are an under-researched form of active case detection used to interrupt transmission chains between countries.

Methods

An individual-based, mathematical metapopulation model of Plasmodium falciparum was used to estimate the effectiveness of border screening posts on total cases in malaria-endemic sub-Saharan Africa.

Results

The implementation of international border posts across 401 sub-national administrative units would avert a median of 7173 (IQR 1075 to 23,550) cases per unit over a 10 year period and reduce PfPR₂

SUBMITTER: Topazian HM 

PROVIDER: S-EPMC12007230 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature