Global, regional and national burdens of major depression disorders and its attributable risk factors in adolescents and young adults aged 10-24 years from 1990 to 2021.

ABSTRACT:

Background

Major depressive disorder (MDD) is an important public health problem among adolescents and young adults, and its increasing prevalence underscores the need for region-specific and age-specific interventions. Despite its increasing burden, comprehensive data on regional and longitudinal trends in MDD among adolescents are scarce. This study analyzed global, regional, and national trends in MDD incidence, prevalence, and disability-adjusted life years (DALYs) among individuals aged 10-24 from 1990 to 2021, while examining differences by gender, age, socio-demographic factors, and emerging risk factors to guide targeted mental health strategies.

Methods

With data from the 2021 Global Burden of Disease Study, we conducted an analysis of age-standardized incidence, pr

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12007280 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature