Executive function at baseline and follow-up in opioid maintenance patients and its relation to psychiatric comorbidity and substance use patterns.

ABSTRACT:

Background

Research investigating executive functions in opioid-dependent patients undergoing opioid maintenance treatment (OMT) is scarce. This study aimed to assess executive function in patients with opioid use disorder at treatment initiation and one-year follow-up, exploring its correlation with psychiatric comorbidity within the patient group. Additionally, associations between executive functions and factors such as age at substance use initiation, duration of substance use, and current substance use were explored.

Methods

Forty-nine adults (mean age: 40.6 [11.4]) with opioid use disorder initiating OMT participated in a naturalistic study with a one-year follow up. Participants underwent subtests of the Delis-Kaplan Executive Function System (D-KEFS) and self-assesse

SUBMITTER: Hogberg JH 

PROVIDER: S-EPMC12007326 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature