Low atypical lymphocyte score as a predictor of non-severe dengue.

ABSTRACT:

Background

Severe dengue has been linked to the presence of atypical lymphocytes, which can be quantified using the Q-flag parameter on a hematology analyzer. A higher atypical lymphocyte count has previously been associated with severe dengue. We aimed to evaluate the feasibility of the atypical lymphocyte score to provide an early prognosis for dengue severity.

Method

A prospective observational study enrolled adult patients admitted to the Infectious Disease ward with a febrile illness of less than 7 days. Blood samples obtained daily until discharge, were processed with XN-20 hematology analyzer with specific attention given to atypical lymphocyte score. Severe dengue cases were classified according to the 2009 World Health Organization Classification.

Results

A t

SUBMITTER: Samudi Raju C 

PROVIDER: S-EPMC12007337 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature