Timed 25-foot walk test is independently associated with cognitive function in multiple sclerosis: a cross-sectional study.

ABSTRACT:

Background

Cognitive impairment (CI) is prevalent among people with multiple sclerosis (PwMS), significantly affecting their quality of life and functional capacity. While the relationship between CI and motor function has been explored in healthy aging and other neurological conditions, its association with upper and lower motor function in PwMS remains underexplored.

Methods

This cross-sectional study analyzed data from 125 PwMS (M_age: 37.6 years; median disease duration: 8 years) to examine cognitive outcomes. Cognitive status was evaluated using the Symbol Digit Modalities Test (SDMT), California Verbal Learning Test-Second Edition (CVLT-II), and Brief Visuospatial Memory Test-Revised (BVMT-R). Motor function was assessed with the 9-Hole Peg Test (9-HPT) and t

SUBMITTER: Mirmosayyeb O 

PROVIDER: S-EPMC12007374 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature