The association between sarcopenic obesity and depression in middle-aged and elderly U.S. adults: insights from the NHANES study.

ABSTRACT:

Purpose

This study aimed to explore the association between sarcopenia, obesity, and sarcopenic obesity with depression in a middle-aged and elderly population in the United States.

Methods

We analyzed data from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2006 and from 2011 to 2018, including 5155 participants aged 45 years and older. Obesity was defined by a body mass index (BMI) ≥ 30 or waist circumference (WC) ≥ 102 cm in men or ≥ 88 cm in women. Sarcopenia was assessed using dual-energy X-ray absorptiometry (DXA) to calculate appendicular skeletal muscle mass index (ASMI), with gender-specific cut-offs. Multivariate logistic regression models adjusted for various covariates were used to assess the associations.

Results

Participants c

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12008062 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature