Transcriptomic insights into the resistance mechanism of Penaeus vannamei against highly lethal Vibrio parahaemolyticus.

ABSTRACT: Highly lethal Vibrio disease (HLVD) caused by a virulent strain of Vibrio parahaemolyticus (Vp_HLVD), which poses a significant threat to Penaeus vannamei post-larvae, leads to substantial mortality and economic losses. To address this challenge, researchers have recently isolated a highly disease-resistant strain of P. vannamei shrimp. However, the underlying mechanisms that could improve disease resistance require further investigation. Our study found that disease-resistant shrimp exhibited a remarkable ability to prevent Vp_HLVD invasion effectively. To unravel the genetic basis of this resistance, we conducted a transcriptomic analysis with susceptible and disease-resistant shrimp at various time points (0, 6, and 12 h) post-infection with Vp_HLVD. Differ

SUBMITTER: Huang Z 

PROVIDER: S-EPMC12008197 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature