Clinical significance of FOXN3 expression in Indian breast cancer patients.

ABSTRACT: Globally, breast cancer is the most common cancer to affect women. There are different molecular and pathological factors that are involved in the uncontrolled proliferation of breast cancer cells. FOXN3 that is member of Forkhead box family proteins is well recognized for having a crucial role in different biological processes and is reported to be dysregulated in various malignancies. The studies to evaluate the significance of the FOXN3 gene in progression of breast cancer are still under progress. We in the current study aim to examine the FOXN3 gene expression in Indian breast cancer patients and find its clinical relevance. FOXN3 expression analysis using RT-PCR, immunohistochemistry, and western blotting was performed in tumor and normal tissue collected from 142 sporadic breast can

SUBMITTER: Massey S 

PROVIDER: S-EPMC12008265 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature