A study on the variation of cytokine and electrolyte levels in rhesus macaques, cynomolgus monkeys, and Assamese macaques.

ABSTRACT:

Background

Non-human primates (NPHs), such as rhesus macaques, cynomolgus monkeys, and Assamese macaques, play a crucial role in biomedical research. However, baseline cytokine and electrolyte data for these three species, particularly data stratified by age and sex, are limited. Therefore, the aim of this study was to establish and analyze age- and sex-specific cytokine and electrolyte profiles in these three species.

Methods

This study included 40 rhesus macaques (21 males, 19 females), 33 cynomolgus monkeys (17 males, 16 females), and 45 Assamese macaques (25 males, 20 females) classified by age (1-5 years, 6-12 years, >13 years) and sex. The levels of 23 immune function indicators and 5 electrolyte indicators were measured.

Results

Among the three monkey species,

SUBMITTER: Duan S 

PROVIDER: S-EPMC12008440 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature