Identifying Features of Resilience to Childhood Maltreatment in Resting-State Connectivity Data From Adults With and Without a History of Mood Disorder.

ABSTRACT:

Background

Childhood maltreatment (CM) is associated with negative mental health outcomes. Many studies conceptualize resilience as experiencing CM without developing psychopathology (primary resilience). However, some people may develop subsequent psychopathology but recover and demonstrate higher global functioning (secondary resilience). This study investigated the role of salience and emotion network (SEN) (including the amygdala, subgenual anterior cingulate cortex, and anterior insula) and cognitive control network (CCN) (including the dorsolateral prefrontal cortex, inferior parietal lobule, and thalamus) connectivity in primary and secondary resilience.

Methods

We examined resting-state functional connectivity in 108 nonclinical control participants and 154 individua

SUBMITTER: Westlund Schreiner M 

PROVIDER: S-EPMC12008536 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature