Impact of diabetes and glycemic status on ventricular-arterial coupling in the general population.

ABSTRACT:

Background/aims

Ventricular-arterial coupling (VAC) plays a crucial role in cardiovascular physiology, affecting cardiac function and arterial properties for optimal organ perfusion. Considering that diabetes mellitus (DM) is a known risk factor for incident heart disease and vascular damage, this study aims to investigate whether changes in VAC due to DM occur earlier, even before the onset of clinically evident cardiovascular disease in the general population.

Methods

This retrospective study included 2,884 participants (mean age 57 years, 48% male) of the Swedish CArdioPulmonary BioImage Study (SCAPIS), where data on echocardiography and Pulse wave velocity (PWV) were available. Of these, 162 individuals (6%) had prevalent type 2 diabetes (DM), and 334 (12%) had prediabet

SUBMITTER: Holm H 

PROVIDER: S-EPMC12008833 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature