Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study.

ABSTRACT:

Background

Emerging evidence suggests that changes in the blood microbes might be associated with cardiovascular disease, especially myocardial infarction (MI). However, some researchers are questioning whether a true "blood microbiome" actually exists. They hypothesized that these microbes may translocate into the bloodstream from the gut or oral cavities. To test this hypothesis, we analyzed the microbial composition, diversity, and potential role in disease progression by comparing blood, gut, and oral microbiota profiles in a cohort of MI patients and healthy controls.

Methods

In this study, 144 samples, including blood, fecal, and saliva, were collected from twenty-four myocardial infarction patients and twenty-four healthy controls. These samples were analyzed using 16

SUBMITTER: Khan I 

PROVIDER: S-EPMC12008866 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature