Multi-contrast 4DMR via MR multitasking: Early clinical experience and implication for liver stereotactic body radiation therapy.

ABSTRACT:

Background

Liver tumors have low contrast on 4DCT. A novel Multitasking (MT)MR imaging technique has been implemented on the MR simulator, providing both T1 and T2-weighted 4DMR images in a single 8-min free-breathing scan for better tumor delineation and motion evaluation. This study reports our early clinical experience of MTMR regarding tumor visibility, motion characteristics, and resultant dosimetry compared to post-contrast 4DCT for liver SBRT.

Methods

Phantom motion validation was performed. Tumor contrast-to-noise ratio (CNR) and motion were analyzed in 54 patients. Replanning for 17 patients (21 tumor volumes) was performed, and planning target volume receiving greater than 90% of the prescription (PTV_V90) was compared based on optimized dose distributions for each

SUBMITTER: April Chau OW 

PROVIDER: S-EPMC12009184 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature