Prevalence and coexistence of locomotive syndrome with reduced mobility and metabolic syndrome: a cross-sectional study of 35,059 Japanese adults.

ABSTRACT: Metabolic syndrome (MetS), marked by visceral obesity, hypertension, hyperglycemia, and dyslipidemia, elevates cardiovascular risk. Locomotive syndrome (LS), characterized by age-related mobility decline, often precedes frailty and sarcopenia. We investigated the prevalence and association between MetS and LS among Japanese middle-aged and older adults. This retrospective cross-sectional study was conducted using clinical records of 35,059 Japanese adults who underwent health check-ups between April 2021 and March 2022. MetS was diagnosed using the modified National Cholesterol Education Program Adult Treatment Panel III criteria, and LS was assessed using the LS risk test, which includes the stand-up test, two-step test, and the 25-question Geriatric Locomotive Function Scale. Among the p

SUBMITTER: Goto C 

PROVIDER: S-EPMC12009296 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature