Appraising non-HDL-C, systolic pressure, and a nomogram-based diagnostic model as auxiliary biomarkers in confirming acute ischemic stroke and transient ischemic attack.

ABSTRACT: Acute ischemic stroke (AIS) is characterized by the abrupt onset of neurological dysfunction stemming from focal brain ischemia, confirmed through imaging evidence of infarction. In contrast, transient ischemic attack (TIA) manifests with neurological deficits in the absence of infarction, with imaging serving as the definitive diagnostic criterion. This study aims to assess the diagnostic value of combining non-high-density lipoprotein cholesterol (non-HDL-C) and blood pressure (BP) in differentiating AIS from TIA. We recruited 207 untreated AIS patients diagnosed within 72 h and 99 age- and gender-matched TIA patients. Upon admission, serum non-HDL-C levels, other lipid profiles, and BP measurements were obtained. Binary logistic regression was employed to identify risk factors, while re

SUBMITTER: Fu Y 

PROVIDER: S-EPMC12009383 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature