Enhanced Performance Monitoring as a Transdiagnostic Risk Marker of the Anxiety and Obsessive-Compulsive Spectrum: The Role of Disorder Category, Clinical Status, Family Risk, and Anxiety Dimensions.

ABSTRACT: In this preregistered study, we investigated the relationship between neural correlates of performance monitoring and disorders of the anxiety and obsessive-compulsive spectrum. Specifically, we aimed at understanding the role of disorder category, clinical status, family risk, and the transdiagnostic symptom dimensions of anxious apprehension and anxious arousal. To this end, we measured event-related potentials (ERPs) of performance monitoring (i.e., error-related negativity, ERN, and correct-response negativity, CRN) in a large sample of 156 participants, including groups of patients with obsessive-compulsive disorder, social anxiety disorder, and specific phobia, as well as a naturalistic control group. Contrary to our initial expectations, we did not observe significant differences in

SUBMITTER: Harpfer K 

PROVIDER: S-EPMC12009682 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature