Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes.

ABSTRACT:

Aim

To assess the association between physical activity (PA), sedentary time (ST), and sleep with body composition, and to explore the effects of reallocating ST to PA or sleep on body composition in individuals with prediabetes and overweight/obesity.

Material methods and results

Baseline data from the PREDIPHONE trial, including 159 participants (mean age 59.6 years) with prediabetes (Fasting Plasma Glucose 100-125 mg/dl) and overweight/obesity (Body Mass Index 27-40 kg/m²), were analyzed. Body composition was assessed via bioelectrical impedance, while PA, ST, and sleep were measured with accelerometry. Linear regression and isotemporal substitution models evaluated associations. Increased ST was positively associated with body fat mass (kg) (β = 0.016; CI 95%: 0.0

SUBMITTER: Torres-Carballo M 

PROVIDER: S-EPMC12009759 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature